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Archive for the ‘Technology’ Category

Lindsay Rosenwald on Abiraterone and the Acquisition of Cougar Biotechnology

In Business, General, Technology on September 26, 2013 at 6:34 am

Lindsay RosenwaldLindsay Rosenwald is a medical doctor and finance expert who specializes in investing in biotechnology and biopharmaceutical research. Lindsay Rosenwald founded Cougar Biotechnology to continue research and development on abiraterone acetate, a drug that combats hormone-resistant prostate cancer. Johnson & Johnson acquired the company in 2009.

Drug development

Development on abiraterone acetate first began in the 1990s, recalls Lindsay Rosenwald. The drug was reviewed by a number of medical investment firms who declined participation. Lab results eventually ended up on the desk of Lindsay Rosenwald, and Cougar Biotechnology then purchased production rights for approximately $500,000.

According to Lindsay Rosenwald, abiraterone acetate enjoyed unparalleled success in its first clinical trials in 2004. The drug proved to induce a decline in prostate-specific antigen levels in patients who had received chemotherapy but were refractory to it. Dr. Lindsay Rosenwald further explains that the U.S. Food and Drug Administration approved the drug after an extremely successful phase 3 clinical study. During the study, the results in the control group were so profound that the trial was halted and placebo participants were given the drug, reports Lindsay Rosenwald.

Abiraterone is an androgen biosynthesis inhibitor (ABI) that directly affects the androgen biosynthesis pathway by inhibiting CYP17 (17α-hydroxylase/C17, 20-lyase). Consequently, androgen biosynthesis is inhibited at 3 sources of testosterone production: the testes, adrenal glands, and prostate tumor tissue. Androgen biosynthesis inhibition results in decreased levels of serum testosterone and other androgens. Androgen-deprivation therapies—such as gonadotropin-releasing hormone (GnRH) analogs or orchiectomy—decrease androgen production in the testes, but do not affect androgen production by the adrenal glands or in the tumor.

As Lindsay Rosenwald reports, abiraterone was approved under the brand name Zytiga and released in April 2011. Zytiga’s approval came after clinical studies of nearly 1,200 late-stage prostate cancer patients showed the overall survival rate was significantly extended after taking the drug, says Dr. Lindsay Rosenwald.

Company acquisition

Lindsay Rosenwald reports that in July 2009, Johnson & Johnson completed its acquisition of Cougar Biotechnology. The acquisition took place after Johnson & Johnson purchased approximately 20,150,000 shares of Cougar Biotechnology stock through a short-form merger.

Johnson & Johnson spent approximately $1 billion to procure Cougar Biotechnology. At the time, Lindsay Rosenwald reports that Cougar Biotechnology was in the process of conducting Phase III clinical trials for abiraterone acetate.

Today, Cougar Biotechnology operates as a subsidiary of Johnson & Johnson and works alongside Ortho Biotech Oncology Research & Development. Lindsay Rosenwald reports that Ortho Biotech is also a Johnson & Johnson company and operates under the umbrella of Centocor Research & Development.

The future of abiraterone

Dr. Lindsay Rosenwald reports that abiraterone acetate may also be indicated to treat advanced breast cancer. Studies performed at the University of London’s Institute of Cancer Research have shown promising results. According to the Institute of Cancer Research website, abiraterone acetate may be most useful for women with estrogen receptor positive breast cancer, says Dr. Lindsay Rosenwald.

Lindsay Rosenwald reports that Zytiga is slated to become a multibillion-dollar pharmaceutical in the coming years and is proud to have been a pioneer of its success. Thousands of lives have been prolonged thanks to the drug, and Lindsay Rosenwald believes that many more will be prolonged or saved in the future.

Cougar Biotechnology was founded to focus on finding medical assets with considerable intrinsic value, says Lindsay Rosenwald. The company achieved its goal by offering a notable new alternative in advanced oncological medication.

The American Spirit of Possibility

In Technology on April 23, 2012 at 5:20 am

A crowning achievement of modern America is a single event that was televised on July 20th, 1969. Many readers may remember that day, but many more were not yet born. It was a day when America proved again that anything is possible. It was a day heralded by a now iconic astronaut as:

“One small step for man; one giant leap for mankind.”

If you have not guessed yet, that man was Neil Armstrong, and the occasion was the moment that man first set food on the moon, wearing the spacesuits of our own American astronauts. But that day – that achievement – reaches deeper than a single moment by a spacecraft. It would not have been possible without the dedication of thousands of Americans working together.

Landing on the moon was an emblematic moment that represented years of engineering, scientific achievement, and cooperation on the part of countless Americans. From President Kennedy’s call to action at Rice University in 1962, it took Americans less than a decade to walk on the moon. From family members of the crew to the number crunchers and physicists at NASA, landing on the moon was a unifying collaboration that raised the spirits of Americans everywhere and reminded us that we can reach the stars, as long as we have a vision.

There was an astounding amount of meticulous labor that was poured into the Apollo moon mission. Mr. Armstrong’s carefully chosen words convey a wise and unifying sentiment. America, though acting as a leader in the world, acts on behalf of all mankind. This historic moment proved that the beauty of American cooperation is not just in the quality of our accomplishments as a nation, but also in the spirit of unity and welcome that those achievements convey to the whole world.

Many citizens consider the American space program a shining example of the resolve and genius of the American people. While American history is decorated with momentous events, both laudable and terrible, there was an event that unified all people and all nations in wonderment and awe. That event was mankind’s first step on the moon, accomplished by the cooperation of our American space program.

Landing on the moon electrified the world with a sense of unity and pride in human achievement. People across the globe were able to gaze in wonderment at the moon footage, listen to Neil Armstrong’s proclamation that this was a “giant leap for mankind.” This moment in 1969 went beyond nationality and ethnicity. Forgotten were the political distinctions of nations and cold war politics. Landing on the moon was an accomplishment for the entire world.

Incredible Discoveries on Lifetime with Lori Leeland

In Home and Family, Marketing, Technology on March 6, 2012 at 12:50 pm
Incredible Discoveries

Incredible Discoveries

The following segment aired on Incredible Discoveries on Lifetime Television. Joining Incredible Discoveries was Lori Leeland, to discuss Hamilton Beach True Air Ultra UV Air Purifier


Incredible Discoveries on Lifetime Television:
Germs are everywhere in your home. Every day dirt, dust, dust-mite debris, mold spores, smoke, pet dander, pollen, and other allergens fill the air all around us. But now you can do something to help keep a cleaner and happier home. Incredible Discoveries introduces The Hamilton Beach True Air Ultra UV Air Purifier, which purifies the air around you.

With a digital display, a 2-stage air filtration and Hamilton Beach True Air Ultra UV Air Purifier germicidal light, this 3 way air treatment system is effective at removing a wide range of impurities from the air including pet dander, pollen, dust mite debris, mold spores, smoke, and more! Incredible Discoveries will show you how it even takes cooking odors out of the air. Like bacon cooking in the morning, it removes the smell within a few minutes. Incredible Discoveries agrees that you won’t have that smell throughout the house the rest of the day.

Incredible Discoveries learns about the Airsmart system and special Hamilton Beach True Air Ultra UV Air Purifier germicidal light from Lori Leeland. Leeland, from Hamilton Beach Laboratory, provides Incredible Discoveries with a scenario of the product’s benefits.

Incredible Discoveries: You hear so much about outdoor air pollution that I don’t think anyone realizes that indoor air pollution can also be a huge problem.

Leeland: Yes, it is a serious problem. With the Hamilton Beach True Air Ultra UV Air Purifier I can show you how dirty indoor air really is. By putting the Hamilton Beach True Air Ultra UV Air Purifier in different rooms in a newly built home for thirty days, you will be amazed of what we’re going to find.

Seen on Incredible Discoveries:
A home was built two years ago and as soon as the Hamilton Beach True Air was plugged in and set to “auto”, it registered “poor air quality”. It would be hard to imagine the air in an older house, compared to this one, built two years prior. The owner placed the Air Purifier in the baby’s room and placed the settings on “auto”. The air quality read “poor”. Right away, the fan sped up and cleaned the entire room within 15 minutes. The air quality status then registered “good”.

When it was first turned on, the status bar was maxed out. It was impossible to know that air was that bad. After turning it on and letting it run for a couple hours, the status moved all the way to “clear”. Incredible Discoveries agrees that the filter actually cleans the air in the room and makes it seem brighter and cleaner.

Incredible Discoveries: I am amazed at all the positive effects that this little system exhibits. The Hamilton Beach True Air Ultra UV Air Purifier is truly the solution to air purification in your home! Air is something we sometimes take for granted. It’s very easy for Incredible Discoveries viewers not to be proactive and take the steps needed to clean something that they don’t really see. Incredible Discoveries observes that more and more people are worried about the quality of the air that why and their family breathe with impurities in the air these days, like pollen, dust, pet dander, and smoke.

Leeland: With the true air ultra UV air purifier, it’s so easy. Just plug it in and watch it actually purify your air within a 200 square foot area! It’s perfect for your home, condo, apartment, family room, bedroom, home office, or basement. The space saving design fits into any home décor and allows for placement against a wall for discrete operation.

ABOUT INCREDIBLE DISCOVERIES
Incredible Discoveries is a marketing firm focusing on direct response infomercial production and online presence development. Incredible Discoveries is a division of O2 Media, Inc., and produces The Balancing Act, one of O2’s most successful shows, airing daily on Lifetime. In addition to Incredible Discoveries’ 43,000 sq.ft. production facility, the firm offers full post production capabilities to tweak and refine their high quality television marketing campaigns. Incredible Discoveries offers a unique and fresh approach to the industry and through its 20 years of experience has created partnerships with some of the world’s leading manufacturers.

On Off Digital World’s New iPads and Net books

In Technology on June 17, 2010 at 6:39 pm

On Off Digital World has observed that the realm of portable computers has evolved with significant changes in user needs. Computer users expect different things from computers these days, adds On Off Digital World, than they did before the Internet was widely used. On Off Digital World says the Internet era has made email, chatting, VoiP calls and web browsing into commonplace computing essentials.

Technology has come far enough, says On Off Digital World, that the simplest of today’s computers are Internet capable. For access to the Internet, explains On Off Digital World, computer users used to be caught between the portability of Internet ready phones and the bulk of home computers. Something too small sacrificed usability, while something too big sacrificed practicality. Even laptop computers, notes On Off Digital World, can weigh as much as 10 pounds. The evolution of computing needs, says On Off Digital World, has prompted innovative responses from hardware and software manufacturers.

The consumer electronics market, continues On Off Digital World, has adapted to these computing needs. On Off Digital World says that the rise of net book computers exemplifies the way technology has adapted to advanced Internet use. The recent launch of Apple’s iPad, adds On Off Digital World, and its trend setting sales figures confirms the arrival of a new Internet based computing era. The best way to be equipped for the new computing era, says On Off Digital World, is to have a net book or an iPad.

Many customers and interested readers ask On Off Digital World, what is the difference between iPads and net books? “Net book” is an umbrella term used to describe a wide family of miniature laptop computers capable of everyday Internet based tasks. Except for a few differences, namely in price, size and style, says On Off Digital World, the Apple iPad does the same everyday tasks of a net book. On Off Digital World adds that these tasks include watching movies during travel, cataloging photographs and surfing the web in wi-fi hot spots. On Off Digital World adds that the iPad is slimmer and sleeker than any net book on the market. At the same time all net books, adds On Off Digital World, are cheaper than iPads and have considerably more storage space.

Contact On Off Digital World at:
485 5th Avenue
New York, NY 10017
212-573-6827

Carnegie Digital Computers | Guide to Informed Electronics Purchases

In Professionals, Technology, Uncategorized on May 25, 2010 at 6:40 pm

All people want to make good decisions with their money. That’s why
Carnegie Digital Computers has compiled the most important and crucial information for those considering buying a new electronic device. According to Carnegie Digital Computers, there are certain things consumers need to know in order to spend their money wisely.

When buying electronics, Carnegie Digital Computers suggests that customers begin by reading Consumer Reports. These official reports detail consumer experiences with certain products, says Carnegie Digital Computers. Such information leads to more informed purchases, which is better for both the buyer and seller. Carnegie Digital Computers lets customers know that the most reliable data on any electronic is available through consumer ratings.

Carnegie Digital Computers also urges buyers to consider purchasing a refurbished electronic device. Refurbs can offer huge discounts compared to the original price. The key is to make sure the product is factory-refurbished, says Carnegie Digital Computers. This is the only way to ensure that the product has a decent manufacturing history. Carnegie Digital Computers explains that these products should also come with a valid warranty in order to provide a good deal to buyers.
Customers may also want to consider purchasing extras for the product. Carnegie Digital Computers says that some electronics stores may not offer add-on memory cards or data cables. Many times, buyers do not need such extra products to receive full functionality of the electronic, but it’s always a good idea to consider.

According to Carnegie Digital Computers, buying products from brands with a history of products with superior performance is usually a good choice. Although many people are wary of big-name brands because of price, Carnegie Digital Computers says that most of these companies make great electronic products.
In general, Carnegie Digital Computers says that the best rule of thumb to use when shopping for electronics is to take the time to find the product that is best for you. Ask questions and do research and Carnegie Digital Computers knows that you will enjoy your new electronics purchase.

Chiro8000 Chiropractic Electronic Medical Record Software Tips: Choosing the Right EMR EHR Tool

In Technology on March 15, 2010 at 3:34 pm

The team at Chiro8000 knows that good patient care is the basis for a successful chiropractic office. Beautiful furnishings, elaborate advertising strategies, and efficient administrative practices may bring in new patients, but they won’t come back unless they believe they are receiving the best patient care available.

While many chiropractors focus on remaining current with the latest advancements in preventive and curative medicine, Chiro8000 says that most are not aware of specific chiropractic electronic medical record software tips that should be considered in their continuing education. Chiro8000 adds that learning how to choose the right EMR-EHR tools has a direct impact on providing the best patient care.

Off-the-rack solutions do not lend themselves to the personalized attention that today’s patient expects, points out Chiro8000. The ability to chart electronically and provide patients with timely billing will make future visits more productive. Additionally, software features like those found in the Chiro8000 software enhance the claims process and remove unnecessary confusion often experienced in antiquated practices.

  • Chiro8000 can be tailored to the specific needs of your office
  • Chiro8000 contains a user-friendly interface
  • Chiro8000 is known for their excellent 24/7 technical support
  • Chiro8000 provides hands-on assistance to make the learning curve easier
  • Chiro8000 team members are responsive to feedback and suggestions

While technology will never replace the relationship between doctor and patient, it can definitely serve to increase patient satisfaction. And as Chiro8000 points out, that is sure to lead to more referrals and a reputation for putting patients first. In the end, a smoother running office utilizing Chiro8000 allows for the kind of growth and expansion that most chiropractors desire.

The Chiro8000 software solution by Forte Systems has a proven record of accomplishment of helping chiropractors become more productive and successful in their efforts to provide the best patient care possible. With thousands of satisfied clients and years of experience, Chiro8000 provides the partnership that can streamline patient care. Visit http://www.Chiro8000.com or call 800-456-2622 for a closer look.

Anthony Schwartz is the president of Chiro8000. Founded in 1983, the Chiro8000 software company has been providing affordable and cutting edge applications specifically for the Chiropractic Profession. Tailored to the small to medium sized practice, the Chiro8000 software connects the area of billing, scheduling, office management, marketing EMR/EHR, communication, patient education, collections, and employee management. With over 200 chiropractors that actively consult with the product as well as their alliance with Microsoft technology, the Chiro8000 offers the perfect balance of technology and industry perspective for the profession.

Lafnac Digital Computers | A Guide to Informed Electronics Shopping

In Technology on February 3, 2010 at 2:27 pm

Lafnac Digital Computers knows that shopping for electronics can be both fun and sometimes daunting. With countless products boasting so many features, it can be hard to know where to start. Lafnac Digital Computers suggests that shoppers begin by reading. When shopping for electronics, read as many reviews as you can find about the product that you are interested in. If you don’t have time to read them all, then Lafnac Digital Computers says to make a point to read at least three. Try to find reviews from different sources that include both corporate and customer sources. With a realistic idea of the pros and cons of each product, Lafnac Digital Computers is sure you will more knowingly choose the product best suited for you.

Let’s say you are shopping for a personal DVD player for your young child. You know that you want something simple and fun, with a good viewing screen. Several personal DVD players sold at Lafnac Digital Computers have children’s themes. But read about these cartoon theme DVD players. Find out what kinds of features are sacrificed for the decoration on the outside of the DVD player. Lafnac Digital Computers has DVD players in all price ranges, and some of them might be perfect for your youngster. Again, reminds Lafnac Digital Computers, start by reading about various DVD players online. Equipped with information you can find a DVD player that will provide you with years of quality entertainment.

Lafnac Digital Computers also offers a comprehensive line of digital cameras. It is impressive how many brands and styles of digital camera are available. To prevent yourself from being overwhelmed by a parade of digital cameras, ask an associate at Lafnac Digital Computers for some comparison-shopping assistance. Comparison-shopping is the smartest way to single out the digital camera that is right for you. Compare prices, features, and sizes of digital cameras. Take a moment to stop by Lafnac Digital Computers to see and examine the different cameras themselves. Lafnac Digital Computers believes that an informed shopper is a happy shopper.

Shop for gadgets at Lafnac Digital Computers, your home for consumer electronics. Lafnac Digital Computers is packed with products and fully staffed with helpful experts that will help you find the information you need to make a satisfying electronics purchase.

E-stealth: Your Digital Ears on the Web

In Technology on October 22, 2009 at 6:32 pm

Lawrenceville, GA, October 20, 2009 – There are times in life when discretion is the watchword. Times when you need to know about the activities of people who would not otherwise tell you. Perhaps you wonder if your kids are texting while driving. Maybe your employees are sending company secrets. E-stealth can help you take care of this kind of business. E-stealth is a leading online retailer of mobile phone spy software.

The mobile phone spy industry is a new addition to cyberspace, but it is growing at an amazing rate. The demand is high for quality private surveillance software, like E-stealth’s product line. With the ability to directly download mobile phone spy software form the E-stealth website, E-stealth puts the tools of law enforcement officials and private investigators into your own hands.

Do you feel that your child is abusing their cell phone privileges? Or maybe you worry that your child is using drugs with objectionable friends. E-stealth offers a full range of software and equipment to help you find out what kids try to hide from parents. E-stealth even provides drug and semen detection kits for identifying problem signs of troubled youth. Get the peace of mind that only knowledge can provide.

Visit E-stealth and find out what you deserve to know.

Contact:
E-Stealth.com, LLC
950 Herrington Rd.
Suite C-179
Lawrenceville, GA 30044
http://www.e-stealth.com

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